Tag: Hematology
PharmaSignal — Hematology therapeutic area
Novo Nordisk preps filings for sickle cell drug etavopivat
Pharmaphorum
Novo Nordisk has claimed a key win in its head-to-head race with Agios to bring an oral PKR activator to the market for sickle cell disease.
Novo’s late-stage sickle cell win piles pressure on competitors
BioSpace
Novo Nordisk’s etavopivat elicited a 27% drop in vaso-occlusive crises and 48.7% hemoglobin response after 24 weeks, creating “separation amongst PK class candidates,” Truist analysts said on Monday.
Merck Chopped $1B Off Terns’ Offer After Seeing Updated Leukemia Data
BioSpace
Another bidder, which remains unidentified, dropped out of the bidding process.
Agios mulls early FDA filing for sickle cell therapy
Pharmaphorum
Agios is planning to file its sickle cell disease candidate mitapivat with the FDA under the accelerated pathway within the next few months.
Merck to buy Terns in $6.7B bet on a ‘differentiated’ leukemia drug
BioPharma Dive
If consummated, the deal would hand Merck a treatment that could challenge Novartis fast-selling Scemblix.
Karyopharm myeloma drug yields mixed data in myelofibrosis trial
BioPharma Dive
Xpovio combined with Incyte s Jakafi helped on one key measure but missed on other goal in a disorder that, by one analyst s estimates, could triple the company s revenue.