Category: M&A / Deals

PharmaSignal — M&A / Deals

Lilly exits Rigel alliance, adding to RIPK1 scrap heap

BioSpace

Eli Lilly and Rigel Pharmaceuticals partnered in February 2021 to advance a pair of RIPK1 blockers, but the pharma in October last year pulled the plug on one of these programs for central nervous sys

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MSD-backed Ray locks in $125m to back eye drug pipeline

Pharmaceutical Technology

Ray’s MSD and Novo Holdings-backed Series B will shed light on the potential of the company’s vision restoration gene therapy pipeline.

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BioAegis and Prenosis partner for inflammatory disease therapies

Pharmaceutical Business Review

The collaboration will evaluate biomarkers and patient subgroups with improved responses to BioAegis’ gelsolin therapy, a critical immune regulatory protein that aims to rebalance inflammation without

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BioAegis and Prenosis partner for inflammatory disease therapies

Pharmaceutical Technology

BioAegis Therapeutics has entered a strategic partnership with Prenosis to advance AI-driven precision medicine for inflammatory diseases.

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Tortugas debuts with $106M and brain drugs from Hansoh, Eisai

BioPharma Dive

Led by former Sage Therapeutics executives Jeff Jonas and Al Robichaud, the company is starting out with a portfolio of neurological medicines in clinical testing.

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Tortugas takes neuro deep dive with $106M to develop Eisai, Hansoh programs

BioSpace

With programs from Eisai and Hansoh Pharmaceutical in hand, Tortugas Neuroscience has emerged with hopes of delivering daily oral treatments to patients with central nervous system conditions.

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Eli Lilly doubles down on in vivo with $7bn Kelonia buyout

Pharmaceutical Technology

Lilly now has a lentiviral and LNP-based platform for in vivo delivery under its belt, which could broaden the company’s chance of success.

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Asahi Kasei acquires German company Aicuris

Pharmaceutical Business Review

The move comes after Asahi Kasei signed a definitive agreement to acquire all issued shares of Aicuris for approximately 780m ($920.7m) earlier this year.

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Asahi Kasei acquires German company Aicuris

Pharmaceutical Technology

Asahi Kasei has completed its acquisition of Aicuris Anti-infective Cures, a German biopharmaceutical company.

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Lilly boosts ‘in vivo’ cell therapy capabilities with Kelonia buyout

BioPharma Dive

Worth up to $7 billion, Lilly s second recent acquisition of a company in the space is centered around a cell therapy that s currently in early-stage testing for multiple myeloma.

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Lilly adds gene delivery technology to CAR T in up to $7B Kelonia deal

BioSpace

After entering the CAR T space in February, Eli Lilly is “jumping into in vivo CAR-T with both feet” with the acquisition of Kelonia Therapeutics and its gene delivery technology.

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Update: Lilly makes $7bn bid for in vivo CAR-T firm Kelonia

Pharmaphorum

Eli Lilly is paying $3.25bn upfront for in vivo CAR-T therapy developer Kelonia, with another $3.75bn on offer if its candidates perform as hoped.

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UCB to purchase Neurona and NRTX-1001 for $1.15bn

Pharmaceutical Business Review

The deal value comprises an upfront payment of up to $650m and up to $500m in future milestones.

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UCB to purchase Neurona and NRTX-1001 for $1.15bn

Pharmaceutical Technology

UCB has signed a definitive agreement to acquire Neurona Therapeutics in a deal worth up to $1.15bn, adding the latter’s lead asset NRTX-1001 to its epilepsy portfolio.

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UCB cuts $1.15bn deal to buy epilepsy biotech Neurona

Pharmaphorum

UCB has dipped its toe into the M A waters once again with an agreement to buy US biotech Neurona and its cell therapy for a common form of epilepsy.

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Kailera makes history with record-breaking $625m IPO

Pharmaceutical Technology

Kailera’s IPO will allow the biotech to take oral and injectable forms of its lead candidate, ribupatide, through late-stage obesity trials.

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Obesity biotech Kailera’s record-breaking IPO

Pharmaphorum

When Kailera revealed its plans for an IPO last month, there was a feeling that it could be huge – and that expectation has now been fulfilled.

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UPDATE: Kailera breaks biotech IPO record with $625M debut

BioSpace

Obesity-focused Kailera Therapeutics debuted on the Nasdaq Friday after raising a record $625 million, beating Moderna’s $600 million from 2018.

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Daiichi Sankyo and Interna partner for MNM-targeted delivery solutions

Pharmaceutical Business Review

The agreement involves Daiichi Sankyo Research Institute Boston and aims to assess the use of Interna’s MNM technology as a delivery enhancer for therapeutic modalities.

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Aligos and Xiamen Amoytop sign deal for HBV therapy

Pharmaceutical Technology

Aligos Therapeutics and Xiamen Amoytop Biotech are to develop and commercialise pevifoscorvir sodium in Greater China for chronic HBV infection.

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