Biotech IPOs stayed at slow pace, but grew larger in the first quarter of 2026

BioPharma Dive

The six companies that have priced initial public offerings so far banked a median of $287.5 million, a figure far surpassing what s been observed over a similar timeframe in prior years, according to

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AZ considers filings for long-acting Strensiq follow-up

Pharmaphorum

AstraZeneca’s long-acting Strensiq follow-up efzimfotase alfa has hit the mark in children with rare disease HPP, but the data in adults is unclear.

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S16 Ep40: FDA Approval Insights: Zongertinib for HER2 TKD-Mutated NSCLC: With Julia Rotow, MD; and Martin Dietrich, MD, PhD

OncLive Podcast

In today’s episode, we spoke with Julia Rotow, MD, and Martin Dietrich, MD, PhD.

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Blackstone closes $6.3B fund for life sciences investing

BioPharma Dive

It’s the biggest life sciences private fund ever raised, coming in nearly 40% larger than its Blackstone predecessor vehicle.

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Kardigan Blood Pressure Drug Proves Hypothesis Despite Split Phase 2 Readout

BioSpace

While tonlamarsen missed one of two co-primary endpoints, Kardigan says the drug has shown a clinically meaningful effect on blood pressure, supporting advancement into Phase 2b.

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Biogen Bounces Back With FDA Nod for High-Dose Spinal Muscular Atrophy Drug

BioSpace

The FDA rejected the high-dose regimen of Spinraza in September last year due to manufacturing concerns.

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Biogen’s Lupus Drug Reduces Disease Activity, Further Deresking I&I Pipeline

BioSpace

William Blair hailed a positive readout in cutaneous lupus erythematosus as a turning point for Biogen, while RBC Capital analysts called the results “another derisking step” for the company’s immunol

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One in four diabetics has undiagnosed heart failure; study

Pharmaphorum

A study has found that undiagnosed heart failure can be detected in people with high-risk diabetes using a simple, GP-led care pathway.

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The Top Pharmacy Benefit Managers of 2025: Market Share and Key Industry Developments

Drug Channels

Three is still the magic number for pharmacy benefit managers (PBMs).

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Amgen’s BiTE for lung cancer backed for EU approval

Pharmaphorum

Amgen’s fast-growing bispecific T-cell engager Imdylltra should be cleared as a second-line therapy for small cell lung cancer, said the CHMP.

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Trustworthy AI in clinical oversight

BioPharma Dive

AI can accelerate clinical work and preserve traceability, but only if users can trust it.

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Otsuka grows in neuroplastogens with $1.225bn Transcend buy

Pharmaphorum

Otsuka has agreed to acquire Transcend Therapeutics and its MDMA-based neuroplastogen drug candidate for PTSD, heading for phase 3 trials.

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Lilly puts up to $2.75bn into Insilico alliance

Pharmaphorum

Insilico has once again added to its roster of big pharma partners, signing a deal with Eli Lilly that includes a $115m upfront payment.

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S16 Ep38: Live Tumor Board: Precision Pathways Transforming Patient Care in Advanced NSCLC

OncLive Podcast

In this podcast, experts Narjust Florez, MD, FASCO; David Carbone, MD, PhD; and Edward Garon, MD, MS; discuss the use of KRAS-, NRG1-, MET-, and ROS1-targeting agents to transform patient care in adva

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Otsuka picks up PTSD drug with $700M Transcend buy

BioPharma Dive

The buyout, which includes another $525 million in floated payouts, hands Otsuka a medicine it sees as a possibly paradigm-shifting therapy in psychiatry.

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AstraZeneca lung drug gets ‘surprise’ win in COPD trials

BioPharma Dive

The treatment, tozorakimab, succeeded where other similar therapies failed and could help a broader group of COPD patients than Dupixent.

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Novartis targets Xolair successor in buyout of startup Excellergy

BioPharma Dive

Worth up to $2 billion, the deal is centered around a drug that could lead to faster and more complete control of allergic conditions than Novartis and Roche s popular medicine.

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The Rare Journey Needs a Special Pharmacy Partner

Drug Channels

Today’s guest post is from Bansi Nagji, Chief Executive Officer at PANTHERx Rare.

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