Category: Regulatory

PharmaSignal — Regulatory

Telomir seeks FDA approval for Telomir-1 to treat breast cancer

Pharmaceutical Business Review

The IND includes results from completed toxicology, pharmacology, and manufacturing studies necessary for regulatory assessment.

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FDA points to liver injury with Amgen’s Tavneos

Pharmaphorum

The FDA has raised the pressure on Amgen to withdraw vasculitis drug Tavneos from the market with a report linking serious side effects to the drug.

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Telomir seeks FDA approval for Telomir-1 to treat breast cancer

Pharmaceutical Technology

Telomir Pharmaceuticals has submitted an IND application to the FDA for Telomir-1, its lead candidate targeting advanced and metastatic TNBC.

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AZ considers filings for long-acting Strensiq follow-up

Pharmaphorum

AstraZeneca’s long-acting Strensiq follow-up efzimfotase alfa has hit the mark in children with rare disease HPP, but the data in adults is unclear.

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S16 Ep40: FDA Approval Insights: Zongertinib for HER2 TKD-Mutated NSCLC: With Julia Rotow, MD; and Martin Dietrich, MD, PhD

OncLive Podcast

In today’s episode, we spoke with Julia Rotow, MD, and Martin Dietrich, MD, PhD.

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Biogen Bounces Back With FDA Nod for High-Dose Spinal Muscular Atrophy Drug

BioSpace

The FDA rejected the high-dose regimen of Spinraza in September last year due to manufacturing concerns.

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Amgen’s BiTE for lung cancer backed for EU approval

Pharmaphorum

Amgen’s fast-growing bispecific T-cell engager Imdylltra should be cleared as a second-line therapy for small cell lung cancer, said the CHMP.

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FDA clears Denali drug in ‘clear step’ for rare disease biotechs

BioPharma Dive

The approval of Denali s Hunter syndrome treatment, Avlayah, comes after a series of drug rejections and delays that had led to criticism of the FDA s stance on rare disease therapies.

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FDA seeks feedback on voucher program; Study data lift ‘overhang’ on Insmed shares

BioPharma Dive

Industry executives can share their views on the national priority program at a June meeting.

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Pfizer, Valneva to seek approval of Lyme disease vaccine despite mixed study results

BioPharma Dive

The partners said the shot produced clinically meaningful efficacy despite missing its main study objective, a finding they blamed on a lower-than-expected rate of infections during the trial.

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