- Dr Weiss on the Role of Breast Imaging in Breast Cancer Treatment Decision-Makingby OncLive articles on November 14, 2024
Anna Weiss, MD, discusses the significance of various imaging modalities in patients with breast cancer.
- Dr Herbst on the Evolution of EGFR Inhibition in Lung Cancerby OncLive articles on November 14, 2024
Roy S. Herbst, MD, PhD, discusses advances in EGFR inhibition throughout the past several decades in patients with lung cancer.
- FDA Approval Insights: Zolbetuximab for CLDN18.2+ HER2-Negative Gastric and GEJ Adenocarcinomaby OncLive articles on November 14, 2024
Dr Ajani discusses the FDA approval of frontline zolbetuximab plus chemo for unresectable or metastatic, HER2–, CLDN18.2+ gastric or GEJ adenocarcinoma.
- FDA Approves Nilotinib Tablets Without Mealtime Restrictions for CMLby OncLive articles on November 14, 2024
The FDA has approved nilotinib tablets without mealtime restrictions for select patients with chronic myeloid leukemia.
- 2024 Updates in GI Cancer Feature FLOT Combinations, Restricted FDA Approvals by PD-L1 Expression, and Moreby OncLive articles on November 14, 2024
Yelena Y. Janjigian, MD, highlights key takeaways and data from 2024 in the gastric and GEJ cancer field.
- Sacituzumab Tirumotecan Shows Antitumor Activity in Previously Treated Endometrial, Ovarian Cancersby OncLive articles on November 14, 2024
Sacituzumab tirumotecan monotherapy demonstrated antitumor activity with a manageable safety profile in previously treated endometrial and ovarian cancers.
- Fox Chase Cancer Center Researchers Find Differences in the Gut Microbiomes of Bladder Cancer Patientsby OncLive articles on November 14, 2024
A new study by researchers at Fox Chase Cancer Center and other institutions adds to that body of research, finding that there are significant differences in the microbiomes of patients who developed bladder cancer compared to those who were healthy.
- NXP800 Demonstrates Single-Agent Activity in ARID1a+ Platinum-Resistant Ovarian Cancerby OncLive articles on November 14, 2024
NXP800 generated antitumor activity as monotherapy in platinum-resistant ovarian cancer harboring ARID1a mutations.
- Eftilagimod Alpha Plus Pembrolizumab/Chemo Generates Improved Survival Trends in Advanced NSCLCby OncLive articles on November 14, 2024
Eftilagimod alpha plus pembrolizumb and chemotherapy generated favorable survival data in nonsquamous NSCLC.
- Belantamab Mafodotin Plus Bortezomib/Dexamethasone Extends OS in R/R Myelomaby OncLive articles on November 14, 2024
Belantamab mafodotin plus bortezomib and dexamethasone met the key secondary end point of OS in relapsed/refractory multiple myeloma in the DREAMM-7 study.
- Perioperative Durvalumab Plus Chemotherapy Represents the Future of Personalized NSCLC Careby OncLive articles on November 14, 2024
Mark Awad, MD, PhD, and Jonathan Spicer, MD, PhD, discuss the FDA approval of perioperative durvalumab for patients with resectable NSCLC.
- Data for Nivolumab Plus AVD Could Help Harmonize Treatment of Older and Younger Advanced-Stage Hodgkin Lymphomaby OncLive articles on November 14, 2024
Alex F. Herrera, MD, discusses long-term data from nivolumab plus AVD in advanced-stage Hodgkin lymphoma.
- Transposon-Based BAFF CAR T Cells Show Early Efficacy, Safety in R/R Non-Hodgkin Lymphomaby OncLive articles on November 14, 2024
Transposon-engineered BAFF ligand–based CAR T cells induced responses with a tolerable safety profile among 3 patients with relapsed/refractory B-cell NHL.
- Piecing Together the Proper BTK Usage in CLLby OncLive articles on November 13, 2024
Nicole Lamanna, MD, highlights various clinical trials underway evaluating new treatment options for patients with chronic lymphocytic leukemia.
- Clinical Oncology Bridges Gaps Between Medical Oncology, Radiation Oncology, and Clinical Research: With D. Ross Camidge, MD, PhD; and Duncan McLaren, MBBS, BSc, FRCR, FRCPby OncLive articles on November 13, 2024
Drs Camidge and McLaren discuss Dr McLaren’s journey to medical school and his experience as a clinical oncologist with expertise across disciplines.
- Real-World Experience With CAR T Varies From Trials in DLBCLby OncLive articles on November 13, 2024
When evaluating real-world experience, differences in race/ethnicity and among elderly patients with DLBCL appeared different from those seen in clinical trials, highlighting the need for consideration in these patient populations.
- BTK Inhibitors, CAR T-Cell Therapy Drive Paradigm Changes in Follicular Lymphomaby OncLive articles on November 13, 2024
Advancements in FL treatment, including BTK inhibitors and CAR T-cell therapies, offer new hope for relapsed or refractory cases.
- 177Lu-PSMA-I&T Meets rPFS End Point in PSMA+ mCRPCby OncLive articles on November 13, 2024
177Lu-PSMA-I&T improved radiographic progression-free survival vs hormonal therapy in PSMA-positive metastatic castration-resistant prostate cancer.
- Retrospective Data Show Pacritinib Improves TSS in Transfusion-Dependent Myelofibrosisby OncLive articles on November 13, 2024
A retrospective study showed pacritinib improved symptoms in transfusion-dependent myelofibrosis.
- Tamibarotene Plus Azacitidine Fails to Improve CR Rates in High-Risk, RARA+ MDSby OncLive articles on November 13, 2024
SELECT-MDS-1 will be discontinued after failing to meet its primary end point of improved CR rates with tamibarotene/azacitidine in high-risk, RARA+ MDS.
- Momelotinib Wins Canadian Approval for Myelofibrosis With Anemiaby OncLive articles on November 13, 2024
Health Canada has approved momelotinib for the treatment of splenomegaly and/or disease-related symptoms in myelofibrosis with moderate-to-severe anemia.
- Dr Moreno on the Pharmacodynamics of CLN-619 in Advanced Solid Tumorsby OncLive articles on November 13, 2024
Victor Moreno, MD, PhD, discusses insights into the pharmacodynamic activity of CLN-619 for patients with advanced solid tumors.